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Summary Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide.
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Summary Tyr1161 in full-length IGF-1R is equivalent toTyr1131 in signal peptide cleaved IGF1R, and Tyr1185 in full-length Insulin Receptor is equivalent to Tyr1146 in signal peptide cleaved Insulin Receptor.

Summary Clone D6C4 and D3E7 directed to different antigenic determinants. Kd is 8.1 x 10⁻⁸M. This antibody reacts with insulin/proinsulin but does not react with free C-peptide.