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Summary The 3DT-52.5 TcR idiotype in Mouse

Summary This antibody has been pre-adsorbed against Mouse, Chicken, Cow, Goat, Guinea pig, Hamster, Horse, Rabbit, Rat and Sheep serum proteins to ensure minimal cross-reactivity. Cross-reactivity with other species, however, is possible.

Summary This antibody recognizes the SC5b-9 complex of around 330 kDa. Both the classical and alternative complement pathways result in the formation of the cytolysis inducing C5b-9 complex. This complex is composed of 190 kDa C5b, which is bound to cells via 71 kDa C9. Sublytic assembly of C5b-9 on plasma membranes induces cell cycle activation and survival. The binding of C5b-9 to the 75 kDa S-protein (or vitronectin) in the fluid phase prevents C5b-9 from assembling on the plasma membrane, deactivating it and forming the SC5b-9 complex. SC5b-9 is stable in vitro and is, therefore, a reliable indicator of terminal complement pathway activation.

Summary This antibody recognizes both native and recombinant bovine IFN gamma.