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Summary Recognizes Hepatitis B surface antigen, subtypes ad & ay. Does not cross-react with normal human serum.

Summary Reacts with residues 132-145 [CQDPRVRGLYFPAGG] of the 42 kDa preS2 HBV protein. This sequence represents a B cell epitope.

Summary Clone [H6F5] and clone [H3A4] are directed to different antigenic determinants.

Summary This antibody recognizes following Hepatitis B virus (HBV) subtypes: ayw2, ayw3, ayw4, ayr, adw2, adw4, adrq+, adrq-. Hepatitis B surface antigen (HBsAg) is a marker of infectivity. Specificity of the antibody HB3 was verified by ELISA on panel of virus subtypes identified on International Workshop on HBsAg Subtypes (Paris, April 1975). The antibody HB3 does not cross-block with the antibody HB5.