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Summary Recognizes the CD28 (44 kDa) human cell surface disulfide-linked, homodimeric glycoprotein. The antibody reacts with human CD28-transfected murine T-cell hybridoma, PHA-activated blasts and IL-6 dependent plasmacytoma lines. It cross reacts with rhesus monkey PBL. The antibody blocks CD28/B7 (CD80) mediated cell-cell adhesion. It binds to the CDR domain in a CDR1 dependent manner. It enhances CD3 monoclonal antibody-induced T-cell proliferation. May be used in adhesion and co-stimulation studies.

CX3CR1 antibody Cat No. GTX27200

4 References

KO/KD Orthogonal

Summary Recombinant and natural rat CX3CR1
KO/KD validation is based on published data (PMID: 29367702).

Iba1 (isoform 1 and 3) antibody, C-term Cat No. GTX89792

5 References

Orthogonal

Summary This antibody is expected to recognize isoform 1 (NP_116573.1) and isoform 3 (NP_001614.3).

CD69 antibody Cat No. GTX37447

5 References

KO/KD

Summary KO/KD validation is based on published data (PMID: 27876794).