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Summary The full-length EGFR includes the 24 aa signal peptide that is cleaved during EGFR maturation. The Tyr1173 of mature EGFR is equivalent to Tyr1197 of uncleaved EGFR.

Summary This antibody is raised against a common region among splicing variants in the cytoplasmic tail domain (CTD) of MUC1-C. Therefore, it is possible to detect various splicing variants, regardless of MUC-1's structure of extracellular region.

Summary Its epitope is resistant to digestion by trypsin and chymotrypsin. This antibody selectively interferes with lymphocyte binding to lymph node, mucosal and synovial endothelium.